Is the left side of the offense faster than the right side this year?

IDK about speed, but I run Ed McCaffrey on the left side most of the time as he is my WR1 and I seem to notice the AI will blatantly interfere with him when he gets a step on them and it never gets called by the refs. McCaffrey even has a big fit about it. In this case the "it's in the game" has never been more true.

No but there are scenarios where your players will run slower depending on the formation